{ "cells": [ { "attachments": {}, "cell_type": "markdown", "metadata": {}, "source": [ "# Spatial Hotspot" ] }, { "attachments": {}, "cell_type": "markdown", "metadata": {}, "source": [ "Spatial hotspot is a tool for identifying informative genes or gene modules in a single-cell dataset. Importantly, 'informative' here is defined based on how well a gene’s variation agrees with certain cell metric - some similarity mapping between cells.\n", "\n", "Genes which are informative are those whose expression varies in similar way among cells which are nearby in the given metric." ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "